The best way to get to the festival is by public transport. Most of the installations are near some metro stations, most typically at lines A and B. You can also choose a tram, preferably lines no. 9, 13, 15, 17, 18 for the route Karlín lines no. 3, 8 and 24.
If you are not from Prague or you are from further suburbs, take advantage of one of the adjacent public car parks and take the bus to the downtown.